New Nanoparticles Deliver Therapy Brain-Wide, Edit Alzheimer’s Gene In Mice
Researchers at UW–Madison have engineered silicone nanoparticles to cross the blood-brain barrier in mice to deliver brain-wide gene editing therapy for Alzheimer’s disease.
Researchers at UW–Madison have engineered silicone nanoparticles to cross the blood-brain barrier in mice to deliver brain-wide gene editing therapy for Alzheimer’s disease.
University of Wisconsin Department of Ophthalmology and Visual Sciences faculty members and staff will present at the 2023 Association of University Professors of Ophthalmology (AUPO) Annual Meeting in San Diego, CA January 24 – 28, 2023. The four-day event offers support, information and leadership opportunities to department chairs, program directors, faculty members in other educational …
The Department of Ophthalmology and Visual Sciences is saddened by the loss of longtime professor and beloved department leader, Thomas Stevens, MD. Stevens died December 26, 2022, at the age of 84.
A current clinical trial could lead to approval of a first-ever treatment option for patients with geographic atrophy (GA) secondary to age-related macular degeneration, a progressive, irreversible, and devastating eye disease.
Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a “handshake” that may show the cells are ready for trials in humans with degenerative eye disorders.
PubMed ID: 32672544 Author(s): Bradfield Y, Barbosa T, Blodi B, Tompson SW, McLellan GJ, Struck M, Young TL. Comparative intraoperative anterior segment OCT findings in pediatric patients with and without glaucoma. Ophthalmol Glaucoma. 2019 Jul – Aug;2(4):232-239. doi: 10.1016/j.ogla.2019.04.006. Epub 2019 May 7. PMID 32672544 Journal: Ophthalmology. Glaucoma, Volume 2, Issue 4, 2019 PURPOSE To …
PubMed ID: 23347981 Author(s): Gajbhiye V, Gong S. Lectin functionalized nanocarriers for gene delivery. Biotechnol Adv. 2013 Sep-Oct;31(5):552-62. doi: 10.1016/j.biotechadv.2013.01.005. Epub 2013 Jan 21. Review. PMID 23347981 Journal: Biotechnology Advances, Volume 31, Issue 5, 2013 Gene therapy has emerged as one of the most promising therapeutic methods to treat various diseases. However, inadequate gene transfection …
PubMed ID: 33206009 Author(s): Miller NP, Aldred B, Schmitt MA, Rokers B. Impact of amblyopia on the central nervous system. J Binocul Vis Ocul Motil. 2020 Oct-Dec;70(4):182-192. doi: 10.1080/2576117X.2020.1841710. Epub 2020 Nov 18. PMID 33206009 Journal: Journal Of Binocular Vision And Ocular Motility, Volume 70, Issue 4, 2020 Amblyopia is a common perceptual disorder resulting …
PubMed ID: 19202557 Author(s): Lim J, Ali ZM, Sanders RA, Snyder AC, Eells JT, Henshel DS, Watkins JB 3rd. Effects of low-level light therapy on hepatic antioxidant defense in acute and chronic diabetic rats. J Biochem Mol Toxicol. 2009 Jan-Feb;23(1):1-8. doi: 10.1002/jbt.20257. PMID 19202557 Journal: Journal Of Biochemical And Molecular Toxicology, Volume 23, Issue 1, …
PubMed ID: 18752309 Author(s): Lim J, Sanders RA, Yeager RL, Millsap DS, Watkins JB 3rd, Eells JT, Henshel DS. Attenuation of TCDD-induced oxidative stress by 670 nm photobiomodulation in developmental chicken kidney. J Biochem Mol Toxicol. 2008 Jul-Aug;22(4):230-9. doi: 10.1002/jbt.20233. PMID 18752309 Journal: Journal Of Biochemical And Molecular Toxicology, Volume 22, Issue 4, 2008 2,3,7,8-Tetrachlorodibenzo-p-dioxin …