PubMed ID: 10230600 Author(s): Levin LA. Intrinsic survival mechanisms for retinal ganglion cells. Eur J Ophthalmol. 1999 Jan-Mar;9 Suppl 1:S12-6. Review. PMID 10230600 Journal: European Journal Of Ophthalmology, Volume 9 Suppl 1, 1999 Retinal ganglion cells (RGCs) undergo programmed cell death (apoptosis) after axonal injury. This cell death is mediated by several mechanisms, including deprivation …
PubMed ID: 11592527 Author(s): Levin LA. Animal and culture models of glaucoma for studying neuroprotection. Eur J Ophthalmol. 2001 Jul-Sep;11 Suppl 2:S23-9. Review. PMID 11592527 Journal: European Journal Of Ophthalmology, Volume 11 Suppl 2, 2001 PURPOSE Neuroprotection aims to treat nervous system disease by maintaining the health and function of neurons. The final proof of …
PubMed ID: 28986311 Author(s): Lawlor M, Danesh-Meyer H, Levin LA, Davagnanam I, De Vita E, Plant GT. Glaucoma and the brain: trans-synaptic degeneration, structural change, and implications for neuroprotection. Surv Ophthalmol. 2018 May – Jun;63(3):296-306. doi: 10.1016/j.survophthal.2017.09.010. Epub 2017 Oct 3. Review. PMID 28986311 Journal: Survey Of Ophthalmology, Volume 63, Issue 3, 2018 A recent …
PubMed ID: 10967081 Author(s): Kortuem K, Geiger LK, Levin LA. Differential susceptibility of retinal ganglion cells to reactive oxygen species. Invest Ophthalmol Vis Sci. 2000 Sep;41(10):3176-82. PMID 10967081 Journal: Investigative Ophthalmology & Visual Science, Volume 41, Issue 10, Sep 2000 PURPOSE Retinal light exposure is a source of oxidative stress, and retinal cells contain molecules …
PubMed ID: 10980770 Author(s): Nork TM, Poulsen GL, Nickells RW, Ver Hoeve JN, Cho NC, Levin LA, Lucarelli MJ. Protection of ganglion cells in experimental glaucoma by retinal laser photocoagulation. Arch Ophthalmol. 2000 Sep;118(9):1242-50. PMID 10980770 Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 118, Issue 9, Sep 2000 OBJECTIVE To test a hypothesis …
PubMed ID: 10870514 Author(s): Dutkiewicz R, Albert DM, Levin LA. Effects of latanoprost on tyrosinase activity and mitotic index of cultured melanoma lines. Exp Eye Res. 2000 May;70(5):563-9. PMID 10870514 Journal: Experimental Eye Research, Volume 70, Issue 5, May 2000 The intraocular pressure-lowering drug latanoprost, a phenyl-substituted analogue of prostaglandin F2 alpha (PGF2 alpha), increases …
PubMed ID: 10690841 Author(s): Levin LA, Gragoudas ES, Lessell S. Endothelial cell loss in irradiated optic nerves. Ophthalmology. 2000 Feb;107(2):370-4. PMID 10690841 Journal: Ophthalmology, Volume 107, Issue 2, Feb 2000 OBJECTIVE Radiation optic neuropathy usually occurs months to years after exposure of the anterior visual pathways to ionizing radiation. It is characterized by high signal …
PubMed ID: 10529787 Author(s): Schwartz M, Yoles E, Levin LA. ‘Axogenic’ and ‘somagenic’ neurodegenerative diseases: definitions and therapeutic implications. Mol Med Today. 1999 Nov;5(11):470-3. Review. PMID 10529787 Journal: Molecular Medicine Today, Volume 5, Issue 11, Nov 1999 Neurodegenerative diseases are characterized by a relentless loss of specific groups of neuronal subtypes. Many of these diseases …
PubMed ID: 10565524 Author(s): Weinreb RN, Levin LA. Is neuroprotection a viable therapy for glaucoma? Arch Ophthalmol. 1999 Nov;117(11):1540-4. Review. PMID 10565524 Journal: Archives Of Ophthalmology (Chicago, Ill. : 1960), Volume 117, Issue 11, Nov 1999 Treatment of glaucoma continues to be directed at lowering intraocular pressure to decrease the likelihood of disease progression. In …
PubMed ID: 10529974 Author(s): Levin LA. Neuro-ophthalmologic diagnosis and therapy of central nervous system trauma. Neurosurg Clin N Am. 1999 Oct;10(4):623-30, viii. Review. PMID 10529974 Journal: Neurosurgery Clinics Of North America, Volume 10, Issue 4, Oct 1999 Careful examination and judicious use of neuroimaging will lead to the initiation of appropriate management for injuries of …